4-Desmethoxy Omeprazole-d3
Catalog No. A70404

4-Desmethoxy Omeprazole-d3 is a deuterium-labeled form of 4-Desmethoxy Omeprazole, the active metabolite of the proton pump inhibitor Omeprazole. This compound primarily targets the CYP2C19 enzyme, exhibiting competitive inhibition with an inhibition constant (Ki) ranging from 2 to 6 μM. It has significant biological activity, including the suppression of gastric acid secretion and the inhibition of growth in both Gram-positive and Gram-negative bacteria. This reagent is valuable for studies involving drug metabolism, pharmacokinetics, and antimicrobial activity.
Chemical Information
| Catalog Num | A70404 |
|---|---|
| M. Wt | 318.41 |
| Formula | C16H14D3N3O2S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1794759-05-9 |
| Synonyms | |
| SMILES | CC(C=C(C=N1)C)=C1CS(C2=NC3=CC(OC([2H])([2H])[2H])=CC=C3N2)=O |
Biological Activity
| Description | 4-Desmethoxy Omeprazole-d3 is a deuterium-labeled form of 4-Desmethoxy Omeprazole, the active metabolite of the proton pump inhibitor Omeprazole. This compound primarily targets the CYP2C19 enzyme, exhibiting competitive inhibition with an inhibition constant (Ki) ranging from 2 to 6 μM. It has significant biological activity, including the suppression of gastric acid secretion and the inhibition of growth in both Gram-positive and Gram-negative bacteria. This reagent is valuable for studies involving drug metabolism, pharmacokinetics, and antimicrobial activity. |
|---|
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


