Product Data Sheet
Calcitroic acid-13C
Catalog No. A70417
Calcitroic acid-13C is a stable isotope-labeled derivative of Calcitroic acid, serving as a vitamin D receptor (VDR) agonist. It effectively activates VDR-mediated transcription, contributing to various biological responses associated with vitamin D metabolism. As the principal metabolite of 1,25-dihydroxyvitamin D3, Calcitroic acid is predominantly found in the liver and mucosal tissues of murine models, highlighting its physiological relevance. This compound exhibits metabolic stability and possesses low toxicity, making it suitable for diverse research applications in vitamin D biology and its implications in disease.
Chemical Information
| Catalog Num | A70417 |
|---|---|
| M. Wt | 375.51 |
| Formula | C2213CH34O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1637678-42-2 |
| Synonyms | |
| SMILES | C[C@@]12[C@](CC[C@]2([H])[C@H](C)C[13C](O)=O)([H])/C(CCC1)=C/C=C3C([C@H](C[C@@H](C\3)O)O)=C |
Biological Activity
| Description | Calcitroic acid-13C is a stable isotope-labeled derivative of Calcitroic acid, serving as a vitamin D receptor (VDR) agonist. It effectively activates VDR-mediated transcription, contributing to various biological responses associated with vitamin D metabolism. As the principal metabolite of 1,25-dihydroxyvitamin D3, Calcitroic acid is predominantly found in the liver and mucosal tissues of murine models, highlighting its physiological relevance. This compound exhibits metabolic stability and possesses low toxicity, making it suitable for diverse research applications in vitamin D biology and its implications in disease. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
