Product Data Sheet

p,p'-DDE-d8

Catalog No. A70419

main product photo
p,p'-DDE-d8 is a deuterated form of p,p'-DDE, a significant metabolite of the environmental contaminant dichlorodiphenyltrichloroethane (DDT). This compound acts as a potent antagonist of the androgen receptor, exhibiting an IC50 value of 5 μM and a Ki of 3.5 μM. p,p'-DDE-d8 is valuable in biological research for studying receptor interactions and the environmental impact of DDT metabolites on endocrine function.
Chemical Information
Catalog NumA70419
M. Wt326.07
FormulaC14D8Cl4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.93952-19-3
Synonyms4,4'-DDE-d8; p,p'-Dichlorodiphenyldichloroethylene-d8
SMILESCl/C(Cl)=C(C1=C([2H])C([2H])=C(C([2H])=C1[2H])Cl)/C2=C([2H])C([2H])=C(C([2H])=C2[2H])Cl
Biological Activity
Descriptionp,p'-DDE-d8 is a deuterated form of p,p'-DDE, a significant metabolite of the environmental contaminant dichlorodiphenyltrichloroethane (DDT). This compound acts as a potent antagonist of the androgen receptor, exhibiting an IC50 value of 5 μM and a Ki of 3.5 μM. p,p'-DDE-d8 is valuable in biological research for studying receptor interactions and the environmental impact of DDT metabolites on endocrine function.
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