Product Data Sheet
Remdesivir de(ethylbutyl 2-aminopropanoate)
Catalog No. A70554
Remdesivir de(ethylbutyl 2-aminopropanoate) is an impurity of the antiviral agent Remdesivir, a nucleoside analogue primarily targeting viral RNA synthesis. This compound is relevant in assessing the purity and efficacy of Remdesivir, which has demonstrated potent antiviral activity against SARS-CoV and MERS-CoV, with EC50 values of 74 nM in human airway epithelial cells and 30 nM against murine hepatitis virus in delayed brain tumor cells. Research involving this impurity can aid in the development and validation of antiviral therapeutics, particularly in the context of COVID-19.
Chemical Information
| Catalog Num | A70554 |
|---|---|
| M. Wt | 447.34 |
| Formula | C18H18N5O7P |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2607871-93-0 |
| Synonyms | |
| SMILES | N#C[C@@]([C@@H]([C@@H]1O)O)(C2=CC=C3N2N=CN=C3N)O[C@@H]1CO[P](OC4=CC=CC=C4)(O)=O |
Biological Activity
| Description | Remdesivir de(ethylbutyl 2-aminopropanoate) is an impurity of the antiviral agent Remdesivir, a nucleoside analogue primarily targeting viral RNA synthesis. This compound is relevant in assessing the purity and efficacy of Remdesivir, which has demonstrated potent antiviral activity against SARS-CoV and MERS-CoV, with EC50 values of 74 nM in human airway epithelial cells and 30 nM against murine hepatitis virus in delayed brain tumor cells. Research involving this impurity can aid in the development and validation of antiviral therapeutics, particularly in the context of COVID-19. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
