Product Data Sheet
Desmethylazelastine
Catalog No. A70632
Desmethylazelastine is the primary active metabolite of Azelastine, functioning as a selective and high-affinity antagonist of the histamine H1 receptor. With a protein binding rate of 97% and an elimination half-life of 54 hours, it plays a significant role in the pharmacological effects of Azelastine. This compound is valuable for research applications involving allergic rhinitis, asthma, diabetic hyperlipidemia, and studies related to SARS-CoV-2.
Chemical Information
| Catalog Num | A70632 |
|---|---|
| M. Wt | 367.87 |
| Formula | C21H22ClN3O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 47491-38-3 |
| Synonyms | |
| SMILES | O=C1C2=C(C(CC3=CC=C(C=C3)Cl)=NN1C4CCNCCC4)C=CC=C2 |
Biological Activity
| Description | Desmethylazelastine is the primary active metabolite of Azelastine, functioning as a selective and high-affinity antagonist of the histamine H1 receptor. With a protein binding rate of 97% and an elimination half-life of 54 hours, it plays a significant role in the pharmacological effects of Azelastine. This compound is valuable for research applications involving allergic rhinitis, asthma, diabetic hyperlipidemia, and studies related to SARS-CoV-2. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
