Product Data Sheet
2-Hydroxy atorvastatin-d5
Catalog No. A70741
2-Hydroxy atorvastatin-d5 is a stable isotope-labeled form of 2-Hydroxy atorvastatin, a hydroxy metabolite of atorvastatin calcium salt. This compound acts as a potent inhibitor of HMG-CoA reductase, with an IC50 value of 8 nM, making it a valuable tool for studying lipid metabolism and cholesterol regulation. It is primarily utilized in pharmacokinetic studies, metabolic profiling, and the development of analytical methods for atorvastatin and its metabolites.
Chemical Information
| Catalog Num | A70741 |
|---|---|
| M. Wt | 579.67 |
| Formula | C33H30D5FN2O6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 777841-55-1 |
| Synonyms | Atorvastatin impurity K-d5 |
| SMILES | OC(C=CC=C1)=C1NC(C2=C(C(C)C)N(CC[C@@H](O)C[C@@H](O)CC(O)=O)C(C3=CC=C(C=C3)F)=C2C4=C([2H])C([2H])=C([2H])C([2H])=C4[2H])=O |
Biological Activity
| Description | 2-Hydroxy atorvastatin-d5 is a stable isotope-labeled form of 2-Hydroxy atorvastatin, a hydroxy metabolite of atorvastatin calcium salt. This compound acts as a potent inhibitor of HMG-CoA reductase, with an IC50 value of 8 nM, making it a valuable tool for studying lipid metabolism and cholesterol regulation. It is primarily utilized in pharmacokinetic studies, metabolic profiling, and the development of analytical methods for atorvastatin and its metabolites. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
