Product Data Sheet
N-Desethyl Sunitinib-d5 hydrochloride
Catalog No. A70745
N-Desethyl Sunitinib-d5 hydrochloride is a deuterated analog of N-Desethyl Sunitinib, a significant metabolite of the multi-targeted kinase inhibitor, sunitinib. This compound functions primarily as a stable isotope for quantitative analysis in pharmacokinetic studies. It demonstrates potent inhibition of vascular endothelial growth factor receptors (VEGFR) as well as platelet-derived growth factor receptor beta (PDGFRβ) and KIT, making it useful in research involving angiogenesis and tumor progression.
Chemical Information
| Catalog Num | A70745 |
|---|---|
| M. Wt | 411.91 |
| Formula | C20H19D5ClFN4O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1261432-14-7 |
| Synonyms | SU-12662-d5 hydrochloride |
| SMILES | O=C(/C(C1=C2)=C/C3=C(C(C(NCCNC([2H])([2H])C([2H])([2H])[2H])=O)=C(N3)C)C)NC1=CC=C2F.Cl |
Biological Activity
| Description | N-Desethyl Sunitinib-d5 hydrochloride is a deuterated analog of N-Desethyl Sunitinib, a significant metabolite of the multi-targeted kinase inhibitor, sunitinib. This compound functions primarily as a stable isotope for quantitative analysis in pharmacokinetic studies. It demonstrates potent inhibition of vascular endothelial growth factor receptors (VEGFR) as well as platelet-derived growth factor receptor beta (PDGFRβ) and KIT, making it useful in research involving angiogenesis and tumor progression. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
