Product Data Sheet
Captopril EP Impurity J
Catalog No. A70845
Captopril EP Impurity J is a drug metabolite associated with the antihypertensive agent Captopril, a thiol-containing competitive angiotensin-converting enzyme (ACE) inhibitor. With an IC50 of 0.025 μM, it plays a crucial role in the modulation of blood pressure by inhibiting the conversion of angiotensin I to angiotensin II. This impurity is significant for research applications focused on drug metabolism and pharmacokinetics, enabling the study of the metabolic pathways and potential effects of Captopril.
Chemical Information
| Catalog Num | A70845 |
|---|---|
| M. Wt | 259.32 |
| Formula | C11H17NO4S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 64838-55-7 |
| Synonyms | S-Acetylcaptopril |
| SMILES | O=C([C@H]1N(C([C@H](C)CSC(C)=O)=O)CCC1)O |
Biological Activity
| Description | Captopril EP Impurity J is a drug metabolite associated with the antihypertensive agent Captopril, a thiol-containing competitive angiotensin-converting enzyme (ACE) inhibitor. With an IC50 of 0.025 μM, it plays a crucial role in the modulation of blood pressure by inhibiting the conversion of angiotensin I to angiotensin II. This impurity is significant for research applications focused on drug metabolism and pharmacokinetics, enabling the study of the metabolic pathways and potential effects of Captopril. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
