Product Data Sheet

Netupitant metabolite Netupitant N-oxide

Catalog No. A70849

main product photo
Netupitant N-oxide is the primary metabolite of Netupitant, a highly selective antagonist of the neurokinin-1 (NK1) receptor. This compound is crucial for studying the pharmacokinetics and pharmacodynamics of Netupitant, contributing to the understanding of its efficacy and safety profile in clinical settings. It is particularly useful in research focusing on antiemetic therapies and the modulation of pain and anxiety pathways.
Chemical Information
Catalog NumA70849
M. Wt594.59
FormulaC30H32F6N4O2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.910808-11-6
SynonymsNetupitant N-oxide
SMILESCN(CCN1C2=CC(C3=CC=CC=C3C)=C(N(C)C(C(C)(C)C4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4)=O)C=N2)(CC1)=O
Biological Activity
DescriptionNetupitant N-oxide is the primary metabolite of Netupitant, a highly selective antagonist of the neurokinin-1 (NK1) receptor. This compound is crucial for studying the pharmacokinetics and pharmacodynamics of Netupitant, contributing to the understanding of its efficacy and safety profile in clinical settings. It is particularly useful in research focusing on antiemetic therapies and the modulation of pain and anxiety pathways.
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