15-Keto latanoprost acid
Catalog No. A70875

15-Keto latanoprost acid is a metabolite of latanoprost that demonstrates modest biological activity. This compound has been shown to induce a small reduction in intraocular pressure (1 mm Hg) in normal cynomolgus monkeys when administered at a dose of 1 μg/eye. Additionally, 15-keto latanoprost exhibits miotic effects in cat eyes, causing an 8 mm Hg decrease in pupillary diameter at a concentration of 5 μg/eye. Its applications may be relevant for research involving ocular pharmacology and the mechanisms of prostaglandin action.
Chemical Information
| Catalog Num | A70875 |
|---|---|
| M. Wt | 388.50 |
| Formula | C23H32O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 369585-22-8 |
| Synonyms | |
| SMILES | O[C@@H]1[C@@H]([C@H]([C@@H](C1)O)CCC(CCC2=CC=CC=C2)=O)C/C=C\CCCC(O)=O |
Biological Activity
| Description | 15-Keto latanoprost acid is a metabolite of latanoprost that demonstrates modest biological activity. This compound has been shown to induce a small reduction in intraocular pressure (1 mm Hg) in normal cynomolgus monkeys when administered at a dose of 1 μg/eye. Additionally, 15-keto latanoprost exhibits miotic effects in cat eyes, causing an 8 mm Hg decrease in pupillary diameter at a concentration of 5 μg/eye. Its applications may be relevant for research involving ocular pharmacology and the mechanisms of prostaglandin action. |
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


