Product Data Sheet
NAMPT activator-9
Catalog No. A71024
NAMPT activator-9 is an allosteric, non-competitive activator of nicotinamide adenine dinucleotide (NAD+) biosynthesis, targeting the enzyme NAMPT with an EC50 of 3.366 μM. This compound enhances NAMPT's enzymatic activity, leading to increased intracellular NAD+ levels. Furthermore, NAMPT activator-9 has been shown to restore myotube diameter and decrease the expression of muscle atrophy markers Atrogin-1 and MuRF1, making it a valuable tool for research on muscle atrophy and related metabolic disorders.
Chemical Information
| Catalog Num | A71024 |
|---|---|
| M. Wt | 305.33 |
| Formula | C17H15N5O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 931366-46-0 |
| Synonyms | |
| SMILES | O=C(N1CC2=C(C=CC=C2)CC1)C3=CC=C(C4=NNN=N4)C=C3 |
Biological Activity
| Description | NAMPT activator-9 is an allosteric, non-competitive activator of nicotinamide adenine dinucleotide (NAD+) biosynthesis, targeting the enzyme NAMPT with an EC50 of 3.366 μM. This compound enhances NAMPT's enzymatic activity, leading to increased intracellular NAD+ levels. Furthermore, NAMPT activator-9 has been shown to restore myotube diameter and decrease the expression of muscle atrophy markers Atrogin-1 and MuRF1, making it a valuable tool for research on muscle atrophy and related metabolic disorders. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
