Product Data Sheet

2-Methylcitric acid

Catalog No. A71297

main product photo
2-Methylcitric acid is an endogenous metabolite involved in the 2-methylcitric acid cycle. Its accumulation is associated with methylmalonic and propionic acidemias, making it a valuable marker metabolite for these conditions. Additionally, 2-methylcitric acid has been shown to significantly inhibit ADP-stimulated and uncoupled respiration in mitochondria when supported by glutamate, highlighting its potential utility in metabolic research.
Chemical Information
Catalog NumA71297
M. Wt206.15
FormulaC7H10O7
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.6061-96-7
SynonymsMethylcitric acid
SMILESCC(C(O)=O)C(C(O)=O)(O)CC(O)=O
Biological Activity
Description2-Methylcitric acid is an endogenous metabolite involved in the 2-methylcitric acid cycle. Its accumulation is associated with methylmalonic and propionic acidemias, making it a valuable marker metabolite for these conditions. Additionally, 2-methylcitric acid has been shown to significantly inhibit ADP-stimulated and uncoupled respiration in mitochondria when supported by glutamate, highlighting its potential utility in metabolic research.
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