Product Data Sheet
Zaragozic acid A
Catalog No. A71406
Zaragozic acid A is a reversible competitive inhibitor of squalene synthase, acting as an endogenous metabolite. This compound effectively inhibits acute hepatic cholesterol synthesis in mouse models, with an IC50 value of 6 μM. Its application is significant in studies investigating cholesterol metabolism and the regulation of lipid biosynthesis.
Chemical Information
| Catalog Num | A71406 |
|---|---|
| M. Wt | 690.73 |
| Formula | C35H46O14 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 142561-96-4 |
| Synonyms | Squalestatin S1 |
| SMILES | CC[C@@H](C[C@@H](/C=C/C(O[C@@H]1[C@H]([C@]2(O[C@@H]([C@@](C(O)=O)([C@]1(C(O)=O)O2)O)C(O)=O)CCC([C@H]([C@@H](CC3=CC=CC=C3)C)OC(C)=O)=C)O)=O)C)C |
Biological Activity
| Description | Zaragozic acid A is a reversible competitive inhibitor of squalene synthase, acting as an endogenous metabolite. This compound effectively inhibits acute hepatic cholesterol synthesis in mouse models, with an IC50 value of 6 μM. Its application is significant in studies investigating cholesterol metabolism and the regulation of lipid biosynthesis. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
