Product Data Sheet
Lysophosphatidylethanolamines, egg
Catalog No. A71429
Lysophosphatidylethanolamines (LPE) are endogenous lysophospholipids generated through the deacylation of phosphatidylethanolamine by phospholipase A2 (PLA2). LPE is known to enhance ERK1/2 phosphorylation in PC12 cells, an effect that can be attenuated by MEK inhibitors such as U-0126 and PD 98059, as well as the EGFR inhibitor AG-1478. Additionally, LPE promotes neurite outgrowth and increases neurofilament M expression in these cells. This product encompasses various molecular species of lysophosphatidylethanolamine characterized by differing fatty acyl chain lengths at the sn-1 position and a hydroxy group at the sn-2 position, making it suitable for diverse biological research applications.
Chemical Information
| Catalog Num | A71429 |
|---|---|
| M. Wt | |
| Formula | N/A |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 97281-40-8 |
| Synonyms | Lyso-PE (egg); LPE (egg); L-α-lysophosphatidylethanolamine |
| SMILES | [Lysophosphatidylethanolamines, egg] |
Biological Activity
| Description | Lysophosphatidylethanolamines (LPE) are endogenous lysophospholipids generated through the deacylation of phosphatidylethanolamine by phospholipase A2 (PLA2). LPE is known to enhance ERK1/2 phosphorylation in PC12 cells, an effect that can be attenuated by MEK inhibitors such as U-0126 and PD 98059, as well as the EGFR inhibitor AG-1478. Additionally, LPE promotes neurite outgrowth and increases neurofilament M expression in these cells. This product encompasses various molecular species of lysophosphatidylethanolamine characterized by differing fatty acyl chain lengths at the sn-1 position and a hydroxy group at the sn-2 position, making it suitable for diverse biological research applications. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
