Product Data Sheet
Tauro-α-muricholic acid sodium
Catalog No. A71660
Tauro-α-muricholic acid sodium is a sodium salt of a taurine-conjugated primary bile acid that functions as an antagonist of the farnesoid X receptor (FXR) with an IC50 of 28 µM. This compound effectively inhibits FXR signaling mediated by other bile acids. Research applications include studies on Alzheimer's disease, glucose metabolism, and lipid metabolism, providing valuable insights into metabolic regulation and related disorders.
Chemical Information
| Catalog Num | A71660 |
|---|---|
| M. Wt | 537.68 |
| Formula | C26H44NNaO7S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2260905-08-4 |
| Synonyms | T-α-MCA sodium |
| SMILES | C[C@H](CCC(NCCS(=O)(O[Na])=O)=O)[C@H]1CC[C@@]2([H])[C@]3([H])[C@H](O)[C@@H](O)[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C |
Biological Activity
| Description | Tauro-α-muricholic acid sodium is a sodium salt of a taurine-conjugated primary bile acid that functions as an antagonist of the farnesoid X receptor (FXR) with an IC50 of 28 µM. This compound effectively inhibits FXR signaling mediated by other bile acids. Research applications include studies on Alzheimer's disease, glucose metabolism, and lipid metabolism, providing valuable insights into metabolic regulation and related disorders. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
