Product Data Sheet
Estrone sulfate-d4 sodium
Catalog No. A71662
Estrone sulfate-d4 sodium is a deuterium-labeled derivative of Estrone sulfate, primarily utilized as a stable isotope in research. It serves as a precursor to bioactive estrogens, Estrone and Estradiol, through enzymatic conversion in various biological systems. This compound is important for studying estrogen metabolism and signaling pathways, particularly in breast cancer research, where it has been shown to promote the proliferation of mammary tumor cells and influence tumor growth in experimental models. Its role as a substrate for the OATP1B3 transporter also highlights its relevance in pharmacokinetic studies.
Chemical Information
| Catalog Num | A71662 |
|---|---|
| M. Wt | 376.44 |
| Formula | C18H17D4NaO5S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 285979-80-8 |
| Synonyms | |
| SMILES | [2H]C1=C(OS(=O)(O[Na])=O)C([2H])=C(CC[C@]2([H])[C@]3([H])CC[C@@]4(C)[C@@]2([H])CC([2H])([2H])C4=O)C3=C1 |
Biological Activity
| Description | Estrone sulfate-d4 sodium is a deuterium-labeled derivative of Estrone sulfate, primarily utilized as a stable isotope in research. It serves as a precursor to bioactive estrogens, Estrone and Estradiol, through enzymatic conversion in various biological systems. This compound is important for studying estrogen metabolism and signaling pathways, particularly in breast cancer research, where it has been shown to promote the proliferation of mammary tumor cells and influence tumor growth in experimental models. Its role as a substrate for the OATP1B3 transporter also highlights its relevance in pharmacokinetic studies. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
