Product Data Sheet
Resolvin D1-d5
Catalog No. A72111
Resolvin D1-d5 is a deuterium-labeled variant of Resolvin D1, an endogenous pro-resolving mediator of inflammation derived from omega-3 docosahexaenoic acid. Its primary mechanism involves the modulation of neutrophil migration and actin polymerization, effectively inhibiting proinflammatory responses. This compound plays a significant role in reducing TNF-α-mediated inflammation in macrophages and enhancing the phagocytosis of apoptotic cells, making it a valuable tool for studies in inflammation resolution and macrophage biology.
Chemical Information
| Catalog Num | A72111 |
|---|---|
| M. Wt | 381.52 |
| Formula | C22H27D5O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1881277-32-2 |
| Synonyms | RvD1-d5 |
| SMILES | O[C@H](/C=C/C=C\C=C\C=C\[C@H]([C@H](C/C=C\CCC(O)=O)O)O)C/C=C\C([2H])(C([2H])([2H])[2H])[2H] |
Biological Activity
| Description | Resolvin D1-d5 is a deuterium-labeled variant of Resolvin D1, an endogenous pro-resolving mediator of inflammation derived from omega-3 docosahexaenoic acid. Its primary mechanism involves the modulation of neutrophil migration and actin polymerization, effectively inhibiting proinflammatory responses. This compound plays a significant role in reducing TNF-α-mediated inflammation in macrophages and enhancing the phagocytosis of apoptotic cells, making it a valuable tool for studies in inflammation resolution and macrophage biology. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
