Product Data Sheet
SR-4995
Catalog No. A72186
SR-4995 is a selective ligand for α-β-hydrolase domain-containing 5 (ABHD5), promoting lipolysis through the activation of adipose triglyceride lipase (ATGL). By displacing ABHD5 from its inhibitory interaction with perilipin-1 (PLIN1) and perilipin-5 (PLIN5), SR-4995 enhances lipid mobilization in adipose and muscle tissues. This compound is valuable for research exploring metabolic regulation and the mechanisms of lipolysis beyond PKA-dependent signaling pathways.
Chemical Information
| Catalog Num | A72186 |
|---|---|
| M. Wt | 355.45 |
| Formula | C19H21N3O2S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 891509-95-8 |
| Synonyms | CID 16016685 |
| SMILES | O=C1N(C)C2=C(C=CC(NC(NCCCC)=O)=C2)SC3=CC=CC=C31 |
Biological Activity
| Description | SR-4995 is a selective ligand for α-β-hydrolase domain-containing 5 (ABHD5), promoting lipolysis through the activation of adipose triglyceride lipase (ATGL). By displacing ABHD5 from its inhibitory interaction with perilipin-1 (PLIN1) and perilipin-5 (PLIN5), SR-4995 enhances lipid mobilization in adipose and muscle tissues. This compound is valuable for research exploring metabolic regulation and the mechanisms of lipolysis beyond PKA-dependent signaling pathways. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
