Product Data Sheet

N-Desmethylolanzapine

Catalog No. A72397

main product photo
N-Desmethylolanzapine is an active metabolite of the antipsychotic agent olanzapine, primarily targeting dopamine D2 and serotonin 5-HT2A receptors. This compound’s formation is influenced by the activity of human liver flavin-containing monooxygenase 3 (FMO3), making it important for understanding drug metabolism. N-Desmethylolanzapine is utilized in research on antipsychotic drugs, aiding in studies of pharmacological effects and metabolic pathways associated with psychiatric disorders.
Chemical Information
Catalog NumA72397
M. Wt298.42
FormulaC16H18N4S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.161696-76-0
SynonymsN-Demethylolanzapine; LY170055
SMILESCC(S1)=CC2=C1NC3=CC=CC=C3N=C2N4CCNCC4
Biological Activity
DescriptionN-Desmethylolanzapine is an active metabolite of the antipsychotic agent olanzapine, primarily targeting dopamine D2 and serotonin 5-HT2A receptors. This compound’s formation is influenced by the activity of human liver flavin-containing monooxygenase 3 (FMO3), making it important for understanding drug metabolism. N-Desmethylolanzapine is utilized in research on antipsychotic drugs, aiding in studies of pharmacological effects and metabolic pathways associated with psychiatric disorders.
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