Product Data Sheet
TRC210258
Catalog No. A72407
TRC210258 is a potent TGR5 agonist that plays a critical role in modulating glucose and lipid metabolism. This compound enhances energy expenditure by promoting the secretion of glucagon-like peptide-1, leading to improved control of hyperglycemia and dyslipidemia in models of diet-induced obesity. Additionally, TRC210258 has demonstrated the ability to reduce plasma triglycerides and low-density lipoprotein cholesterol levels, thereby positively influencing lipid-related cardiovascular risk factors such as remnant cholesterol and triglyceride clearance. Its application in metabolic research highlights its potential for therapeutic intervention in metabolic disorders.
Chemical Information
| Catalog Num | A72407 |
|---|---|
| M. Wt | 396.80 |
| Formula | C20H14ClFN4O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1431553-15-9 |
| Synonyms | |
| SMILES | O=C(N(C)C1=CC=C(C=C1)Cl)C2=C(N=C3N=CC=CN32)OC4=CC=C(C=C4)F |
Biological Activity
| Description | TRC210258 is a potent TGR5 agonist that plays a critical role in modulating glucose and lipid metabolism. This compound enhances energy expenditure by promoting the secretion of glucagon-like peptide-1, leading to improved control of hyperglycemia and dyslipidemia in models of diet-induced obesity. Additionally, TRC210258 has demonstrated the ability to reduce plasma triglycerides and low-density lipoprotein cholesterol levels, thereby positively influencing lipid-related cardiovascular risk factors such as remnant cholesterol and triglyceride clearance. Its application in metabolic research highlights its potential for therapeutic intervention in metabolic disorders. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
