Product Data Sheet
C18:1 Cyclic LPA
Catalog No. A72459
C18:1 Cyclic LPA is an endogenous metabolite that serves as an analog of the growth factor-like phospholipid mediator, lysophosphatidic acid (LPA). Its distinctive 5-membered ring structure, formed between the sn-2 hydroxy group and the sn-3 phosphate, enables C18:1 Cyclic LPA to modulate various cellular functions. Key biological activities include the inhibition of cell cycle progression, promotion of stress fiber formation, and reduction of tumor cell invasiveness and metastasis. Additionally, it influences the differentiation and survival of neuronal cells, often yielding effects that oppose those induced by LPA, despite engaging similar receptor populations.
Chemical Information
| Catalog Num | A72459 |
|---|---|
| M. Wt | 421.55 |
| Formula | C21H44NO5P |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 799268-69-2 |
| Synonyms | |
| SMILES | CCCCCCCC/C=C\CCCCCCCCOC[C@H]1OP(O)(OC1)=O.N |
Biological Activity
| Description | C18:1 Cyclic LPA is an endogenous metabolite that serves as an analog of the growth factor-like phospholipid mediator, lysophosphatidic acid (LPA). Its distinctive 5-membered ring structure, formed between the sn-2 hydroxy group and the sn-3 phosphate, enables C18:1 Cyclic LPA to modulate various cellular functions. Key biological activities include the inhibition of cell cycle progression, promotion of stress fiber formation, and reduction of tumor cell invasiveness and metastasis. Additionally, it influences the differentiation and survival of neuronal cells, often yielding effects that oppose those induced by LPA, despite engaging similar receptor populations. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
