Product Data Sheet
Dapagliflozin-3-O-β-D-glucuronide
Catalog No. A72592
Dapagliflozin-3-O-β-D-glucuronide is an endogenous metabolite of Dapagliflozin, produced primarily by the enzyme uridine diphosphate glucuronosyltransferase-1A9 (UGT1A9) in the liver and kidney. This compound plays a crucial role in the pharmacokinetics of Dapagliflozin, a selective inhibitor of sodium-glucose co-transporter 2 (SGLT2), which is utilized for improving glycemic control in type 2 diabetes management. Its study is significant in understanding drug metabolism and therapeutic efficacy in diabetic conditions.
Chemical Information
| Catalog Num | A72592 |
|---|---|
| M. Wt | 585.00 |
| Formula | C27H33ClO12 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1351438-75-9 |
| Synonyms | BMS-801576 |
| SMILES | ClC1=C(CC2=CC=C(C=C2)OCC)C=C([C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O[C@]4([C@@H]([C@H]([C@@H]([C@H](O4)C(O)=O)O)O)O)[H])O)C=C1 |
Biological Activity
| Description | Dapagliflozin-3-O-β-D-glucuronide is an endogenous metabolite of Dapagliflozin, produced primarily by the enzyme uridine diphosphate glucuronosyltransferase-1A9 (UGT1A9) in the liver and kidney. This compound plays a crucial role in the pharmacokinetics of Dapagliflozin, a selective inhibitor of sodium-glucose co-transporter 2 (SGLT2), which is utilized for improving glycemic control in type 2 diabetes management. Its study is significant in understanding drug metabolism and therapeutic efficacy in diabetic conditions. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
