Product Data Sheet

Hydroxy bosentan

Catalog No. A72689

main product photo
Hydroxy bosentan is an endogenous metabolite derived from Bosentan, primarily processed by the cytochrome P450 system in the liver. This compound retains 10%-20% of Bosentan's pharmacological activity, serving as a significant contributor to the overall therapeutic effects of the parent compound. Hydroxy bosentan is useful in research focused on metabolic pathways and the pharmacokinetics of endothelin receptor antagonists.
Chemical Information
Catalog NumA72689
M. Wt567.61
FormulaC27H29N5O7S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.253688-60-7
SynonymsRo 48-5033
SMILESCOC1=CC=CC=C1OC2=C(N=C(N=C2OCCO)C3=NC=CC=N3)NS(C4=CC=C(C=C4)C(CO)(C)C)(=O)=O
Biological Activity
DescriptionHydroxy bosentan is an endogenous metabolite derived from Bosentan, primarily processed by the cytochrome P450 system in the liver. This compound retains 10%-20% of Bosentan's pharmacological activity, serving as a significant contributor to the overall therapeutic effects of the parent compound. Hydroxy bosentan is useful in research focused on metabolic pathways and the pharmacokinetics of endothelin receptor antagonists.
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