Ganglioside GD1b Disodium Salt (Bovine Brain)
Catalog No. A72840

Ganglioside GD1b Disodium Salt (Bovine Brain) is an acidic glycosphingolipid that acts as an endogenous metabolite and is characterized by two sialic acid residues connected to an internal galactose unit. This compound is known to facilitate the formation of lipid microdomains through its interaction with cholesterol, thereby influencing intracellular and intercellular signaling. Elevated levels of Ganglioside GD1b have been associated with aging and higher grades of pilocytic astrocytoma, as well as being present in various gliomas, including glioblastomas, primitive neuroectodermal tumors, and anaplastic astrocytomas, highlighting its potential relevance in cancer research.
Chemical Information
| Catalog Num | A72840 |
|---|---|
| M. Wt | 1882.04 |
| Formula | C₈₄H₁₄₆N₄Na₂O₃₉ |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 19553-76-5 |
| Synonyms | Disialoganglioside GD1b; Ganglioside C1; Ganglioside G2 |
| SMILES | O[C@H]1[C@@H](O)[C@@H](CO)O[C@@H](O[C@H]2[C@@H](O)[C@@H](CO)O[C@@H](O[C@@H]3[C@H](O[C@]4(C(O[Na])=O)C[C@H](O)[C@@H](NC(C)=O)[C@H]([C@H](O)[C@H](O[C@]5(C(O[Na])=O)C[C@H](O)[C@@H](NC(C)=O)[C@H]([C@H](O)[C@H](O)CO)O5)CO)O4)[C@@H](O)[C@H](O[C@H]6[C@H](O)[C@@H](O)[C@H](OCC(NC(CCCCCCCCCCCCCCCCC)=O)C(O)/C=C/CCCCCCCCCCCCC)O[C@@H]6CO)O[C@@H]3CO)[C@@H]2NC(C)=O)[C@@H]1O |
Biological Activity
| Description | Ganglioside GD1b Disodium Salt (Bovine Brain) is an acidic glycosphingolipid that acts as an endogenous metabolite and is characterized by two sialic acid residues connected to an internal galactose unit. This compound is known to facilitate the formation of lipid microdomains through its interaction with cholesterol, thereby influencing intracellular and intercellular signaling. Elevated levels of Ganglioside GD1b have been associated with aging and higher grades of pilocytic astrocytoma, as well as being present in various gliomas, including glioblastomas, primitive neuroectodermal tumors, and anaplastic astrocytomas, highlighting its potential relevance in cancer research. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


