Product Data Sheet
C20 Sphingomyelin (d18:1/20:0)
Catalog No. A72988
C20 Sphingomyelin (d18:1/20:0) is a naturally occurring sphingolipid that targets cellular membranes and plays a critical role in various biological processes. It is associated with increased levels in the hippocampus of streptozotocin-induced diabetic rats, showing a positive correlation with insulin resistance in obese human subjects. Additionally, C20 Sphingomyelin (d18:1/20:0) is elevated in the liver of mouse models of Niemann-Pick C1 disease, a neurodegenerative disorder characterized by lysosomal storage of cholesterol and sphingolipids. This compound serves as a valuable tool for studying metabolic disorders and neurodegenerative diseases.
Chemical Information
| Catalog Num | A72988 |
|---|---|
| M. Wt | 759.13 |
| Formula | C43H87N2O6P |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 121999-68-6 |
| Synonyms | N-eicosanoyl-D-erythro-Sphingosylphosphorylcholine; SM(d18:1/20:0) |
| SMILES | CCCCCCCCCCCCCCCCCCCC(N[C@H]([C@H](O)/C=C/CCCCCCCCCCCCC)COP(OCC[N+](C)(C)C)([O-])=O)=O |
Biological Activity
| Description | C20 Sphingomyelin (d18:1/20:0) is a naturally occurring sphingolipid that targets cellular membranes and plays a critical role in various biological processes. It is associated with increased levels in the hippocampus of streptozotocin-induced diabetic rats, showing a positive correlation with insulin resistance in obese human subjects. Additionally, C20 Sphingomyelin (d18:1/20:0) is elevated in the liver of mouse models of Niemann-Pick C1 disease, a neurodegenerative disorder characterized by lysosomal storage of cholesterol and sphingolipids. This compound serves as a valuable tool for studying metabolic disorders and neurodegenerative diseases. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
