Product Data Sheet
Pyrimidine-indole hybrid
Catalog No. A73067
Pyrimidine-indole hybrid is an endogenous metabolite that functions primarily as an antagonist of the Hedgehog signaling pathway through the destabilization of microtubules. This compound demonstrates significant biological activity by inhibiting ciliogenesis and disrupting the stable form of α-tubulin. Its unique mechanism of action has been validated in in vitro cell studies and in zebrafish embryo models, making it a valuable tool for investigating microtubule dynamics and related signaling processes.
Chemical Information
| Catalog Num | A73067 |
|---|---|
| M. Wt | 361.46 |
| Formula | C20H19N5S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 441742-93-4 |
| Synonyms | |
| SMILES | CC(NC1=C2C=CC=C1)=C2/C=N/NC3=C4C5=C(SC4=NC=N3)CCCC5 |
Biological Activity
| Description | Pyrimidine-indole hybrid is an endogenous metabolite that functions primarily as an antagonist of the Hedgehog signaling pathway through the destabilization of microtubules. This compound demonstrates significant biological activity by inhibiting ciliogenesis and disrupting the stable form of α-tubulin. Its unique mechanism of action has been validated in in vitro cell studies and in zebrafish embryo models, making it a valuable tool for investigating microtubule dynamics and related signaling processes. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
