Product Data Sheet

Chlorambucyl-proline

Catalog No. A73208

main product photo
Chlorambucyl-proline is an amino acid derivative exhibiting inhibitory activity against bovine pulmonary vasoconstrictor enzyme. This compound functions as an irreversible inhibitor by forming ester bonds with the enzyme's aspartic or glutamic acid residues, leading to permanent enzyme inactivation. The rate of inactivation by chlorambucyl-proline is influenced by pH, with increased activity observed in the 5-8 range, making it a valuable tool for studying enzymatic regulation and function in physiological pH environments.
Chemical Information
Catalog NumA73208
M. Wt401.33
FormulaC19H26Cl2N2O3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.81050-71-7
Synonyms
SMILESO=C(O)[C@H]1N(C(CCCC2=CC=C(N(CCCl)CCCl)C=C2)=O)CCC1
Biological Activity
DescriptionChlorambucyl-proline is an amino acid derivative exhibiting inhibitory activity against bovine pulmonary vasoconstrictor enzyme. This compound functions as an irreversible inhibitor by forming ester bonds with the enzyme's aspartic or glutamic acid residues, leading to permanent enzyme inactivation. The rate of inactivation by chlorambucyl-proline is influenced by pH, with increased activity observed in the 5-8 range, making it a valuable tool for studying enzymatic regulation and function in physiological pH environments.
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