Product Data Sheet
Lu AF58801
Catalog No. A73251
Lu AF58801 is a selective positive allosteric modulator of the α7 nicotinic acetylcholine receptors, demonstrating potent oral bioavailability and effective brain penetration. This compound has been shown to enhance receptor activity and improve cognitive function in animal models, specifically in a novel object recognition task in mice subjected to subchronic exposure to fluchlorothiazol. Lu AF58801 serves as a valuable tool for investigating the role of α7 nicotinic receptors in cognitive processes and related disorders.
Chemical Information
| Catalog Num | A73251 |
|---|---|
| M. Wt | 325.40 |
| Formula | C20H23NO3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1531592-40-1 |
| Synonyms | |
| SMILES | OC[C@@H](C1=CC=C(C=C1)OCC)NC([C@@H]2[C@@H](C3=CC=CC=C3)C2)=O |
Biological Activity
| Description | Lu AF58801 is a selective positive allosteric modulator of the α7 nicotinic acetylcholine receptors, demonstrating potent oral bioavailability and effective brain penetration. This compound has been shown to enhance receptor activity and improve cognitive function in animal models, specifically in a novel object recognition task in mice subjected to subchronic exposure to fluchlorothiazol. Lu AF58801 serves as a valuable tool for investigating the role of α7 nicotinic receptors in cognitive processes and related disorders. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
