Product Data Sheet

JTV-803 mesylate

Catalog No. A73311

main product photo
JTV-803 mesylate is a selective inhibitor of human factor Xa, functioning as an oral anticoagulant. It demonstrates competitive inhibition with a Ki value of 0.019 μM and an IC50 value of 0.081 μM, showcasing a remarkable specificity over comparable inhibitors. JTV-803 is primarily used in research focused on thrombosis prevention and the modulation of coagulation pathways, making it a valuable tool for studies in cardiovascular and hematological contexts.
Chemical Information
Catalog NumA73311
M. Wt505.59
FormulaC23H31N5O6S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.247131-79-9
Synonyms
SMILESO=C(C1(CCN(CC1)C2=CC=NC=C2)COC3=CC=C4C(CN(CC4)C(N)=N)=C3)O.O=S(O)(C)=O
Biological Activity
DescriptionJTV-803 mesylate is a selective inhibitor of human factor Xa, functioning as an oral anticoagulant. It demonstrates competitive inhibition with a Ki value of 0.019 μM and an IC50 value of 0.081 μM, showcasing a remarkable specificity over comparable inhibitors. JTV-803 is primarily used in research focused on thrombosis prevention and the modulation of coagulation pathways, making it a valuable tool for studies in cardiovascular and hematological contexts.
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