LY 190388
Catalog No. A73335

LY 190388 is a penicillamine-containing enkephalin peptide analog that acts as a μ-opioid receptor agonist. This compound demonstrates significant analgesic effects, as evidenced by its ability to inhibit the writhing response in mice following intracerebroventricular administration. Notably, the analgesic properties of LY 190388 are primarily attributed to its μ receptor activity, while co-administration with the δ receptor antagonist ICI 174864 produces an additive analgesic effect, supporting its potential applications in pain research.
Chemical Information
| Catalog Num | A73335 |
|---|---|
| M. Wt | 615.74 |
| Formula | C30H41N5O7S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 105496-35-3 |
| Synonyms | |
| SMILES | [C@H](CC1=CC=CC=C1)(C(N[C@H](C(C)C)C(O)=O)=O)NC(CNC([C@H](NC([C@H](CC2=CC=C(O)C=C2)N)=O)C(C)(C)S)=O)=O |
Biological Activity
| Description | LY 190388 is a penicillamine-containing enkephalin peptide analog that acts as a μ-opioid receptor agonist. This compound demonstrates significant analgesic effects, as evidenced by its ability to inhibit the writhing response in mice following intracerebroventricular administration. Notably, the analgesic properties of LY 190388 are primarily attributed to its μ receptor activity, while co-administration with the δ receptor antagonist ICI 174864 produces an additive analgesic effect, supporting its potential applications in pain research. |
|---|
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


