Product Data Sheet
MR-16728 hydrochloride
Catalog No. A73346
MR-16728 hydrochloride is an endogenous metabolite that primarily promotes the release of acetylcholine through inhibition of Ca(2+)-ATPase activity in presynaptic membranes. It effectively enhances acetylcholine release and demonstrates significant activity in the presence of low calcium concentrations. Research applications include studying neurotransmitter release mechanisms and analyzing acetylcholine dynamics under various physiological conditions. The compound shows a half-maximal effect at a concentration of 13.5 μM, making it a valuable tool for investigating synaptic transmission and neuromodulation.
Chemical Information
| Catalog Num | A73346 |
|---|---|
| M. Wt | 393.01 |
| Formula | C23H37ClN2O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 207403-36-9 |
| Synonyms | |
| SMILES | O=C(NCCCN1CCCCCC1)C(C2CCCCC2)C3=CC=CC=C3.Cl |
Biological Activity
| Description | MR-16728 hydrochloride is an endogenous metabolite that primarily promotes the release of acetylcholine through inhibition of Ca(2+)-ATPase activity in presynaptic membranes. It effectively enhances acetylcholine release and demonstrates significant activity in the presence of low calcium concentrations. Research applications include studying neurotransmitter release mechanisms and analyzing acetylcholine dynamics under various physiological conditions. The compound shows a half-maximal effect at a concentration of 13.5 μM, making it a valuable tool for investigating synaptic transmission and neuromodulation. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
