Product Data Sheet
Anisperimus
Catalog No. A73387
Anisperimus is an endogenous metabolite that acts as an immunosuppressant by enhancing activation-induced T cell death. It increases the sensitivity of T cells to anti-CD95 antibodies through the activation of caspase-8 and caspase-10 at the death-inducing signaling complex (DISC). Additionally, Anisperimus promotes the differentiation of Foxp3-expressing regulatory CD4 T cells, contributing to the prevention of autoimmunity within the central nervous system. This reagent is valuable for research focused on T cell regulation and autoimmune diseases.
Chemical Information
| Catalog Num | A73387 |
|---|---|
| M. Wt | 401.55 |
| Formula | C18H39N7O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 170368-04-4 |
| Synonyms | LF-150195 |
| SMILES | C[C@@H](N)CCNCCCCNC(OCC(NCCCCCCNC(N)=N)=O)=O |
Biological Activity
| Description | Anisperimus is an endogenous metabolite that acts as an immunosuppressant by enhancing activation-induced T cell death. It increases the sensitivity of T cells to anti-CD95 antibodies through the activation of caspase-8 and caspase-10 at the death-inducing signaling complex (DISC). Additionally, Anisperimus promotes the differentiation of Foxp3-expressing regulatory CD4 T cells, contributing to the prevention of autoimmunity within the central nervous system. This reagent is valuable for research focused on T cell regulation and autoimmune diseases. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
