Product Data Sheet

Rociverine

Catalog No. A73398

main product photo
Rociverine is an anticholinergic agent with a primary mechanism of smooth muscle relaxation, targeting muscarinic receptors. It demonstrates diverse binding modes across five cloned muscarinic receptor types, with its cis stereoisomer exhibiting notably higher affinity than its trans counterpart. The (1R,2R) configuration of Rociverine displays affinities that can exceed 240 times higher, highlighting the significance of the (1S,2S) configuration for binding selectivity. This compound serves as a valuable tool for studying gastrointestinal motility and other smooth muscle-related conditions.
Chemical Information
Catalog NumA73398
M. Wt339.51
FormulaC20H37NO3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.53716-44-2
Synonyms
SMILESO[C@@]1(C2CCCCC2)[C@H](CCCC1)C(OC(C)CN(CC)CC)=O
Biological Activity
DescriptionRociverine is an anticholinergic agent with a primary mechanism of smooth muscle relaxation, targeting muscarinic receptors. It demonstrates diverse binding modes across five cloned muscarinic receptor types, with its cis stereoisomer exhibiting notably higher affinity than its trans counterpart. The (1R,2R) configuration of Rociverine displays affinities that can exceed 240 times higher, highlighting the significance of the (1S,2S) configuration for binding selectivity. This compound serves as a valuable tool for studying gastrointestinal motility and other smooth muscle-related conditions.
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SHIPPING AND STORAGE
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