Rociverine
Catalog No. A73398

Rociverine is an anticholinergic agent with a primary mechanism of smooth muscle relaxation, targeting muscarinic receptors. It demonstrates diverse binding modes across five cloned muscarinic receptor types, with its cis stereoisomer exhibiting notably higher affinity than its trans counterpart. The (1R,2R) configuration of Rociverine displays affinities that can exceed 240 times higher, highlighting the significance of the (1S,2S) configuration for binding selectivity. This compound serves as a valuable tool for studying gastrointestinal motility and other smooth muscle-related conditions.
Chemical Information
| Catalog Num | A73398 |
|---|---|
| M. Wt | 339.51 |
| Formula | C20H37NO3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 53716-44-2 |
| Synonyms | |
| SMILES | O[C@@]1(C2CCCCC2)[C@H](CCCC1)C(OC(C)CN(CC)CC)=O |
Biological Activity
| Description | Rociverine is an anticholinergic agent with a primary mechanism of smooth muscle relaxation, targeting muscarinic receptors. It demonstrates diverse binding modes across five cloned muscarinic receptor types, with its cis stereoisomer exhibiting notably higher affinity than its trans counterpart. The (1R,2R) configuration of Rociverine displays affinities that can exceed 240 times higher, highlighting the significance of the (1S,2S) configuration for binding selectivity. This compound serves as a valuable tool for studying gastrointestinal motility and other smooth muscle-related conditions. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


