Product Data Sheet
LacCer (d18:1/16:0)-d3
Catalog No. A73423
LacCer (d18:1/16:0)-d3 is a deuterium-labeled form of LacCer (d18:1/16:0), a bioactive sphingolipid involved in forming membrane microdomains with Lyn kinase and αi subunits of inhibitory G protein-coupled receptors (GPCRs). This compound is particularly relevant in studies of metabolic disorders, as elevated levels are found in the plasma of insulin-resistant cattle, and it is upregulated in models of Niemann-Pick type C1 disease, a neurodegenerative lysosomal storage disorder. LacCer (d18:1/16:0)-d3 serves as a valuable tool for elucidating the role of sphingolipids in various biological processes and disease pathways.
Chemical Information
| Catalog Num | A73423 |
|---|---|
| M. Wt | 865.20 |
| Formula | C46H84D3NO13 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2097249-92-6 |
| Synonyms | C16 Lactosylceramide (d18:1/16:0)-d3 |
| SMILES | OC[C@@H](O[C@H]([C@@H]([C@H]1O)O)OC[C@@H]([C@H](O)/C=C/CCCCCCCCCCCCC)NC(CCCCCCCCCCCCCCC([2H])([2H])[2H])=O)[C@H]1O[C@@H]2O[C@@H]([C@@H]([C@@H]([C@H]2O)O)O)CO |
Biological Activity
| Description | LacCer (d18:1/16:0)-d3 is a deuterium-labeled form of LacCer (d18:1/16:0), a bioactive sphingolipid involved in forming membrane microdomains with Lyn kinase and αi subunits of inhibitory G protein-coupled receptors (GPCRs). This compound is particularly relevant in studies of metabolic disorders, as elevated levels are found in the plasma of insulin-resistant cattle, and it is upregulated in models of Niemann-Pick type C1 disease, a neurodegenerative lysosomal storage disorder. LacCer (d18:1/16:0)-d3 serves as a valuable tool for elucidating the role of sphingolipids in various biological processes and disease pathways. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
