Product Data Sheet

7,8-Dichloro-1,2,3,4-tetrahydroisoquinoline

Catalog No. A73507

main product photo
7,8-Dichloro-1,2,3,4-tetrahydroisoquinoline is a selective inhibitor of phenylethanolamine N-methyltransferase (PNMT), exhibiting a Ki value of 0.3 μM. This compound is primarily utilized in research exploring psychiatric disorders associated with Alzheimer's disease and Parkinson's disease. Its mechanism of action makes it a valuable tool for studying the role of PNMT in neurodegenerative conditions.
Chemical Information
Catalog NumA73507
M. Wt202.08
FormulaC9H9Cl2N
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.61563-24-4
Synonyms
SMILESClC1=C(Cl)C=CC2=C1CNCC2
Biological Activity
Description7,8-Dichloro-1,2,3,4-tetrahydroisoquinoline is a selective inhibitor of phenylethanolamine N-methyltransferase (PNMT), exhibiting a Ki value of 0.3 μM. This compound is primarily utilized in research exploring psychiatric disorders associated with Alzheimer's disease and Parkinson's disease. Its mechanism of action makes it a valuable tool for studying the role of PNMT in neurodegenerative conditions.
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