Product Data Sheet
BCM-599
Catalog No. A73650
BCM-599 is an endogenous metabolite that functions as a hepatitis B virus (HBV) capsid assembly inhibitor. It demonstrates potent antiviral activity with an IC50 value of 0.88 μM and a CC50 value of 144 μM in HepG2.2.15 cells. When administered in conjunction with lamivudine, BCM-599 exhibits a synergistic effect, enhancing the reduction of viral concentration. This compound is a valuable tool for investigating combined strategies for the treatment of HBV infection.
Chemical Information
| Catalog Num | A73650 |
|---|---|
| M. Wt | 342.15 |
| Formula | C14H10Cl2FN3O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1820763-99-2 |
| Synonyms | |
| SMILES | FC1=CC=C(C=C1)C(NCC(NC2=C(N=C(C=C2)Cl)Cl)=O)=O |
Biological Activity
| Description | BCM-599 is an endogenous metabolite that functions as a hepatitis B virus (HBV) capsid assembly inhibitor. It demonstrates potent antiviral activity with an IC50 value of 0.88 μM and a CC50 value of 144 μM in HepG2.2.15 cells. When administered in conjunction with lamivudine, BCM-599 exhibits a synergistic effect, enhancing the reduction of viral concentration. This compound is a valuable tool for investigating combined strategies for the treatment of HBV infection. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
