Ethylenediaminediacetic acid
Catalog No. A73660

Ethylenediaminediacetic acid (EDDA) serves as a key ligand, effectively enhancing the antiproliferative activities of metal complexes. These complexes demonstrate significant antiproliferative effects in the MCF-7 cancer cell line and exhibit the capacity to interact with DNA, as analyzed through circular dichroism (CD) and electron paramagnetic resonance (EPR) spectroscopy. Additionally, EDDA and its metal complexes can induce cell cycle arrest at the G(0)/G(1) phase, highlighting their potential application in cancer research. Structural analysis of EDDA contributes valuable insights into its biological mechanisms and interactions.
Chemical Information
| Catalog Num | A73660 |
|---|---|
| M. Wt | 176.17 |
| Formula | C6H12N2O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 5657-17-0 |
| Synonyms | N,N-Ethylenediglycine |
| SMILES | C(CNCC(=O)O)NCC(=O)O |
Biological Activity
| Description | Ethylenediaminediacetic acid (EDDA) serves as a key ligand, effectively enhancing the antiproliferative activities of metal complexes. These complexes demonstrate significant antiproliferative effects in the MCF-7 cancer cell line and exhibit the capacity to interact with DNA, as analyzed through circular dichroism (CD) and electron paramagnetic resonance (EPR) spectroscopy. Additionally, EDDA and its metal complexes can induce cell cycle arrest at the G(0)/G(1) phase, highlighting their potential application in cancer research. Structural analysis of EDDA contributes valuable insights into its biological mechanisms and interactions. |
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
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Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


