Product Data Sheet
AZD-6605
Catalog No. A73665
AZD-6605 is a potent, reversible inhibitor targeting matrix metalloproteinases MMP2, MMP9, MMP12, and MMP13, exhibiting high selectivity. This compound was optimized for enhanced activity, solubility, and drug metabolism and pharmacokinetics (DMPK) properties by modifying the zinc hydroxide binding group found in traditional inhibitors. AZD-6605 is valuable for investigating the roles of these metalloproteinases in various biological processes and disease states, making it suitable for research applications in inflammation, cancer, and tissue remodeling studies.
Chemical Information
| Catalog Num | A73665 |
|---|---|
| M. Wt | 483.43 |
| Formula | C18H21F4N3O6S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 893556-15-5 |
| Synonyms | |
| SMILES | O=C1NC([C@](C)(N1)CS(=O)(N2CCC(CC2)OC3=CC=C(C=C3)OC(F)(C(F)F)F)=O)=O |
Biological Activity
| Description | AZD-6605 is a potent, reversible inhibitor targeting matrix metalloproteinases MMP2, MMP9, MMP12, and MMP13, exhibiting high selectivity. This compound was optimized for enhanced activity, solubility, and drug metabolism and pharmacokinetics (DMPK) properties by modifying the zinc hydroxide binding group found in traditional inhibitors. AZD-6605 is valuable for investigating the roles of these metalloproteinases in various biological processes and disease states, making it suitable for research applications in inflammation, cancer, and tissue remodeling studies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
