Product Data Sheet
R1663
Catalog No. A73712
R1663 is a selective inhibitor of factor Xa, demonstrating significant anticoagulant activity without affecting bleeding time. Its pharmacodynamic effects, such as the inhibition of thrombin generation, are dose-dependent, contributing to the prolongation of clotting time in a concentration-dependent manner. R1663 effectively reduces the peak height of thrombin generation and the endogenous thrombin potential, making it a valuable tool for research in coagulation and thrombus formation.
Chemical Information
| Catalog Num | A73712 |
|---|---|
| M. Wt | 519.90 |
| Formula | C24H21ClF3N5O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 865451-66-7 |
| Synonyms | |
| SMILES | O=C([C@H]1CN(CC(F)F)C[C@@H]1C(NC2=CC=C(N3C=CC=CC3=O)C=C2F)=O)NC4=NC=C(Cl)C=C4 |
Biological Activity
| Description | R1663 is a selective inhibitor of factor Xa, demonstrating significant anticoagulant activity without affecting bleeding time. Its pharmacodynamic effects, such as the inhibition of thrombin generation, are dose-dependent, contributing to the prolongation of clotting time in a concentration-dependent manner. R1663 effectively reduces the peak height of thrombin generation and the endogenous thrombin potential, making it a valuable tool for research in coagulation and thrombus formation. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
