Product Data Sheet
ODE-Bn-PMEG
Catalog No. A73728
ODE-Bn-PMEG is an antiviral compound that targets human papillomavirus (HPV) by inhibiting the amplification of viral DNA. Demonstrating robust activity against HPV-11, -16, and -18, ODE-Bn-PMEG effectively reduces transient viral replication in transfected cells without reaching cytotoxic levels. The compound exhibits enhanced uptake in human foreskin fibroblasts and is converted to the active antiviral metabolite PMEG diphosphate in vitro. Additionally, the P-chiral enantiomer of ODE-Bn-PMEG maintains comparable antiviral efficacy, highlighting its potential for use against multiple HPV strains and in local therapeutic applications.
Chemical Information
| Catalog Num | A73728 |
|---|---|
| M. Wt | 675.84 |
| Formula | C35H58N5O6P |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1626364-18-8 |
| Synonyms | |
| SMILES | O=C1N=C(NC2=C1N=CN2CCOCP(OCC3=CC=CC=C3)(OCCOCCCCCCCCCCCCCCCCCC)=O)N |
Biological Activity
| Description | ODE-Bn-PMEG is an antiviral compound that targets human papillomavirus (HPV) by inhibiting the amplification of viral DNA. Demonstrating robust activity against HPV-11, -16, and -18, ODE-Bn-PMEG effectively reduces transient viral replication in transfected cells without reaching cytotoxic levels. The compound exhibits enhanced uptake in human foreskin fibroblasts and is converted to the active antiviral metabolite PMEG diphosphate in vitro. Additionally, the P-chiral enantiomer of ODE-Bn-PMEG maintains comparable antiviral efficacy, highlighting its potential for use against multiple HPV strains and in local therapeutic applications. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
