Product Data Sheet
LY-195448 hydrochloride
Catalog No. A73789
LY-195448 hydrochloride is a phenethanolamine that targets cellular processes during the metaphase of the cell cycle, exhibiting notable anti-tumor activity in various murine tumor models. This compound has shown a favorable safety profile, lacking many common side effects associated with conventional cancer therapies, such as myelosuppression and gastrointestinal toxicity. In phase I clinical trials, LY-195448 hydrochloride resulted in mild and reversible side effects, including hypotension, tachycardia, and tremors, making it a promising candidate in cancer research applications.
Chemical Information
| Catalog Num | A73789 |
|---|---|
| M. Wt | 362.89 |
| Formula | C20H27ClN2O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 111112-18-6 |
| Synonyms | |
| SMILES | NC(C(C=C1)=CC=C1CCC(C)(C)NC[C@@H](C2=CC=CC=C2)O)=O.Cl |
Biological Activity
| Description | LY-195448 hydrochloride is a phenethanolamine that targets cellular processes during the metaphase of the cell cycle, exhibiting notable anti-tumor activity in various murine tumor models. This compound has shown a favorable safety profile, lacking many common side effects associated with conventional cancer therapies, such as myelosuppression and gastrointestinal toxicity. In phase I clinical trials, LY-195448 hydrochloride resulted in mild and reversible side effects, including hypotension, tachycardia, and tremors, making it a promising candidate in cancer research applications. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
