Product Data Sheet
3β,7β-Dihydroxy-5-cholestenoic acid
Catalog No. A73790
3β,7β-Dihydroxy-5-cholestenoic acid is an endogenous metabolite that plays a crucial role in lipid metabolism. Elevated levels of this C27 acid have been associated with Niemann-Pick type C and Niemann-Pick type B diseases, contributing to neuronal toxicity, particularly in oculomotor neurons. This compound is produced through the enzymatic action of hydroxysteroid 11-β dehydrogenase 1 on 3β-hydroxy-7-oxocholest-5-en-(25R)26-oic acid and is valuable for research into lipid-related disorders and neurodegenerative diseases.
Chemical Information
| Catalog Num | A73790 |
|---|---|
| M. Wt | 432.64 |
| Formula | C27H44O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1246298-66-7 |
| Synonyms | |
| SMILES | C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCC[C@@H](C)C(O)=O)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4(C(C[C@H](CC4)O)=C[C@@H]3O)C |
Biological Activity
| Description | 3β,7β-Dihydroxy-5-cholestenoic acid is an endogenous metabolite that plays a crucial role in lipid metabolism. Elevated levels of this C27 acid have been associated with Niemann-Pick type C and Niemann-Pick type B diseases, contributing to neuronal toxicity, particularly in oculomotor neurons. This compound is produced through the enzymatic action of hydroxysteroid 11-β dehydrogenase 1 on 3β-hydroxy-7-oxocholest-5-en-(25R)26-oic acid and is valuable for research into lipid-related disorders and neurodegenerative diseases. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
