Product Data Sheet
MRS4458
Catalog No. A73814
MRS4458 is a selective antagonist of the P2Y14 receptor, demonstrating significant anti-inflammatory activity. This compound effectively modulates neutrophil motility, contributing to its therapeutic potential in inflammatory conditions. Designed through molecular dynamic simulations, MRS4458 exhibits optimized shape and complementarity with the receptor. Its biological efficacy has been validated using fluorescence assays, confirming a robust antagonistic effect against the target receptor.
Chemical Information
| Catalog Num | A73814 |
|---|---|
| M. Wt | 515.51 |
| Formula | C24H20F3N5O3S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2225834-49-9 |
| Synonyms | |
| SMILES | O=C(C1=CC(C2=CC=C(C(NCCCN)=O)S2)=CC(N3N=NC(C4=CC=C(C(F)(F)F)C=C4)=C3)=C1)O |
Biological Activity
| Description | MRS4458 is a selective antagonist of the P2Y14 receptor, demonstrating significant anti-inflammatory activity. This compound effectively modulates neutrophil motility, contributing to its therapeutic potential in inflammatory conditions. Designed through molecular dynamic simulations, MRS4458 exhibits optimized shape and complementarity with the receptor. Its biological efficacy has been validated using fluorescence assays, confirming a robust antagonistic effect against the target receptor. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
