Product Data Sheet
Besigliptin tosylate
Catalog No. A73830
Besigliptin tosylate is a selective DPP-4 inhibitor that enhances metabolic control and β-cell function. It effectively lowers serum DPP-4 activity and improves oral glucose tolerance, demonstrating significant reductions in fasting blood glucose levels and enhanced lipid profiles in diabetic mouse models. Additionally, chronic administration of besigliptin tosylate increases insulin staining in pancreatic islet cells, underscoring its potential to improve β-cell function in therapeutic applications related to diabetes management.
Chemical Information
| Catalog Num | A73830 |
|---|---|
| M. Wt | 537.65 |
| Formula | C25H36FN5O5S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1177460-72-8 |
| Synonyms | SHR117887 |
| SMILES | O=S(O)(C1=CC=C(C=C1)C)=O.O=C(N2[C@@H](C[C@@H](C2)F)C#N)CN[C@@]3(C[C@]4([H])[C@@](C3)([H])CN(C4)C(N(C)C)=O)C |
Biological Activity
| Description | Besigliptin tosylate is a selective DPP-4 inhibitor that enhances metabolic control and β-cell function. It effectively lowers serum DPP-4 activity and improves oral glucose tolerance, demonstrating significant reductions in fasting blood glucose levels and enhanced lipid profiles in diabetic mouse models. Additionally, chronic administration of besigliptin tosylate increases insulin staining in pancreatic islet cells, underscoring its potential to improve β-cell function in therapeutic applications related to diabetes management. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
