Product Data Sheet
(Rac)-PAT-494
Catalog No. A73847
(Rac)-PAT-494 is a type II autotaxin inhibitor that specifically targets the enzyme responsible for the production of lysophosphatidic acid (LPA) in the bloodstream. By antagonizing autotaxin, (Rac)-PAT-494 exhibits promising potential in addressing diseases associated with cancer, fibrosis, and inflammation. It demonstrates high efficacy in biochemical assays and plasma tests, and has been shown to effectively lower plasma LPA levels following oral administration in rat models.
Chemical Information
| Catalog Num | A73847 |
|---|---|
| M. Wt | 349.36 |
| Formula | C20H16FN3O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1781233-72-4 |
| Synonyms | |
| SMILES | FC1=CC=C(CN2C3=CC=CC=C3C4=C2CN(C5C4)C(NC5=O)=O)C=C1 |
Biological Activity
| Description | (Rac)-PAT-494 is a type II autotaxin inhibitor that specifically targets the enzyme responsible for the production of lysophosphatidic acid (LPA) in the bloodstream. By antagonizing autotaxin, (Rac)-PAT-494 exhibits promising potential in addressing diseases associated with cancer, fibrosis, and inflammation. It demonstrates high efficacy in biochemical assays and plasma tests, and has been shown to effectively lower plasma LPA levels following oral administration in rat models. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
