Product Data Sheet

C-Type Natriuretic Peptide (1-53), Porcine, Rat,mouse

Catalog No. A73879

main product photo
C-Type Natriuretic Peptide (1-53), derived from porcine, rat, and mouse sources, acts as a specific activator of particulate guanylate cyclase B (pGC-B), a receptor prevalent in endothelial cells, kidneys, and cardiac tissues. This peptide is known to induce significant anti-fibrotic responses in human cardiac and renal fibroblasts by promoting the synthesis of the secondary messenger cGMP. It is valuable for research focusing on cardiovascular and renal pathophysiology, offering insights into therapeutic strategies for fibrotic diseases.
Chemical Information
Catalog NumA73879
M. Wt5796.68
FormulaC251H414N82O70S3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.129405-72-7
Synonyms
SMILES
Biological Activity
DescriptionC-Type Natriuretic Peptide (1-53), derived from porcine, rat, and mouse sources, acts as a specific activator of particulate guanylate cyclase B (pGC-B), a receptor prevalent in endothelial cells, kidneys, and cardiac tissues. This peptide is known to induce significant anti-fibrotic responses in human cardiac and renal fibroblasts by promoting the synthesis of the secondary messenger cGMP. It is valuable for research focusing on cardiovascular and renal pathophysiology, offering insights into therapeutic strategies for fibrotic diseases.
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