Product Data Sheet

MNI-caged kainate

Catalog No. A73913

main product photo
MNI-caged kainate is a photoprotective derivative of the endogenous neuroactive amino acid kainate, with a primary mechanism of action involving the activation of AMPA receptors. Upon photorelease, it elicits substantial inward currents in Purkinje cells, facilitating the investigation of fast synaptic transmission dynamics. MNI-caged kainate is employed in studies aimed at elucidating synaptic receptor mechanisms, significantly contributing to our understanding of excitatory neurotransmission. Its rapid photorelease kinetics, occurring in the sub-microsecond range, makes it an invaluable tool for real-time studies of synaptic activity.
Chemical Information
Catalog NumA73913
M. Wt323.30
FormulaC14H17N3O6
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1315378-75-6
Synonyms
SMILESO=C(O)[C@H](NC)CC(N1CCC2=C1C([N+]([O-])=O)=CC=C2OC)=O
Biological Activity
DescriptionMNI-caged kainate is a photoprotective derivative of the endogenous neuroactive amino acid kainate, with a primary mechanism of action involving the activation of AMPA receptors. Upon photorelease, it elicits substantial inward currents in Purkinje cells, facilitating the investigation of fast synaptic transmission dynamics. MNI-caged kainate is employed in studies aimed at elucidating synaptic receptor mechanisms, significantly contributing to our understanding of excitatory neurotransmission. Its rapid photorelease kinetics, occurring in the sub-microsecond range, makes it an invaluable tool for real-time studies of synaptic activity.
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SHIPPING AND STORAGE
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