Product Data Sheet
Hydroxy Bosentan-d4
Catalog No. A73981
Hydroxy Bosentan-d4 is a deuterium-labeled derivative of Hydroxy bosentan, a primary metabolite of Bosentan (BOS) that undergoes metabolism via the cytochrome P450 system in the liver. This isotope-labeled compound maintains 10%-20% of BOS's pharmacological activity, making it valuable for studying the metabolism and pharmacokinetics of Bosentan in various biological systems. Hydroxy Bosentan-d4 is suitable for applications in drug metabolism research and isotope labeling studies.
Chemical Information
| Catalog Num | A73981 |
|---|---|
| M. Wt | 571.64 |
| Formula | C27H25D4N5O7S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1065472-91-4 |
| Synonyms | Ro 48-5033-d4 |
| SMILES | COC1=CC=CC=C1OC2=C(OC([2H])([2H])C([2H])([2H])O)N=C(C3=NC=CC=N3)N=C2NS(C4=CC=C(C(C)(C)CO)C=C4)(=O)=O |
Biological Activity
| Description | Hydroxy Bosentan-d4 is a deuterium-labeled derivative of Hydroxy bosentan, a primary metabolite of Bosentan (BOS) that undergoes metabolism via the cytochrome P450 system in the liver. This isotope-labeled compound maintains 10%-20% of BOS's pharmacological activity, making it valuable for studying the metabolism and pharmacokinetics of Bosentan in various biological systems. Hydroxy Bosentan-d4 is suitable for applications in drug metabolism research and isotope labeling studies. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
