Product Data Sheet
GSK-1562590
Catalog No. A74028
GSK-1562590 is a high-affinity antagonist of the uropeptide-II receptor, demonstrating notable selectivity. This compound exhibits significant antagonistic activity across various biological assays and maintains prolonged receptor binding. GSK-1562590 effectively inhibits human urinary peptide-II-induced aortic contraction in rat models, with effects persisting for a minimum of 24 hours. Its properties make it a valuable tool for investigating the role of uropeptide-II in cardiovascular physiology and related metabolic research.
Chemical Information
| Catalog Num | A74028 |
|---|---|
| M. Wt | 581.49 |
| Formula | C30H30Cl2N4O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1003877-55-1 |
| Synonyms | |
| SMILES | NC(C1=CC=CC(C(C=C2)=CC=C2[C@H](CN3CCCC3)N(C)C(CN4C5=CC(Cl)=C(Cl)C=C5OCC4=O)=O)=C1)=O |
Biological Activity
| Description | GSK-1562590 is a high-affinity antagonist of the uropeptide-II receptor, demonstrating notable selectivity. This compound exhibits significant antagonistic activity across various biological assays and maintains prolonged receptor binding. GSK-1562590 effectively inhibits human urinary peptide-II-induced aortic contraction in rat models, with effects persisting for a minimum of 24 hours. Its properties make it a valuable tool for investigating the role of uropeptide-II in cardiovascular physiology and related metabolic research. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
