Product Data Sheet

Rofleponide epimer

Catalog No. A74130

main product photo
Rofleponide epimer is an endogenous metabolite that targets glucocorticoid receptors, exhibiting significant anti-inflammatory activity. It demonstrates high selectivity for lung tissues and effectively binds to the rat thymic glucocorticoid receptor, reinforcing its pharmacological efficacy. Additionally, Rofleponide epimer has a biotransformation rate that is ten times greater than that of similar compounds, highlighting its potential for therapeutic applications in managing inflammatory diseases affecting mucosal surfaces.
Chemical Information
Catalog NumA74130
M. Wt468.53
FormulaC25H34F2O6
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.144459-71-2
Synonyms
SMILESOCC([C@]12[C@@]3([C@@]([C@@]4([H])[C@]([C@H](C3)O)([C@@]5(C([C@H](C4)F)=CC(CC5)=O)C)F)([H])C[C@@]1([H])O[C@@H](O2)CCC)C)=O
Biological Activity
DescriptionRofleponide epimer is an endogenous metabolite that targets glucocorticoid receptors, exhibiting significant anti-inflammatory activity. It demonstrates high selectivity for lung tissues and effectively binds to the rat thymic glucocorticoid receptor, reinforcing its pharmacological efficacy. Additionally, Rofleponide epimer has a biotransformation rate that is ten times greater than that of similar compounds, highlighting its potential for therapeutic applications in managing inflammatory diseases affecting mucosal surfaces.
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